Re: These situations puzzle me.
I think the short answer is not to get into that situation in the first place with a small pair. The 9:1 odds are OK given your roughly 8:1 chance of hitting a set, but then there's a good chance in this case that a set of 4s won't be good enough.
A pair of at least 9s would usually be my own threshold for getting involved UTG + 1. No hard and fast logic to that, except that there's a better chance of you having an overpair and/or being ahead.
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